Hand Eczema: Causes, Types, Treatment and How to Heal Dry, Cracked Hands
Eczema guide
Hand eczema is inflammation of the skin on the hands that causes dryness, redness, cracks, itch and sometimes small blisters. It is very common: about 1 in 7 people get it at some point in life. Most cases are triggered or worsened by water, soap and irritants, so treatment works best when you combine the right cream with protecting your hands every day.
- About 14.5% of people develop hand eczema in their lifetime, and women are affected 1.5 to 2 times more often than men.
- The main types are irritant, allergic contact, atopic and blistering (pompholyx) hand eczema; many people have more than one cause.
- Washing hands 8 to 10 or more times a day raises the risk by about 50%; alcohol hand rub was not linked to a higher risk.
- Emollients, gloves and avoiding triggers are the foundation; doctors add anti-inflammatory creams and, for severe cases, newer treatments.
- See a doctor if it lasts more than a few weeks, keeps coming back, is painful, weeping or infected.

What is hand eczema?
Hand eczema (hand dermatitis) is an inflammatory skin condition of the hands and wrists. It can look like dry, rough, red or darker skin, painful cracks around the fingertips and knuckles, scaling on the palms, or clusters of small itchy blisters along the sides of the fingers.
It is common and often long-lasting. A systematic review of 66 studies covering more than 568,000 people found a lifetime prevalence of 14.5%, with about 9% affected in any given year. More than a third had moderate or severe disease, and around a third also had a history of atopic eczema (Quaade et al., 2021). Doctors usually call it chronic hand eczema when it lasts longer than 3 months or comes back at least twice a year (Thyssen et al., 2022).
What are the types of hand eczema?
| Type | Typical signs | Common cause |
|---|---|---|
| Irritant contact | Dry, red, chapped skin on the backs of hands and between fingers | Frequent washing, water, detergents, cleaning products, friction |
| Allergic contact | Itchy rash where an allergen touches the skin, may spread to wrists | Rubber glove chemicals, preservatives, fragrance, nickel, hair dye |
| Atopic | Dry, itchy patches, often with eczema elsewhere | Weak skin barrier, history of atopic eczema |
| Vesicular (pompholyx) | Small, deep, very itchy blisters on palms and finger sides | Often recurrent; heat, sweat and stress can trigger flares |
| Hyperkeratotic | Thick, scaly, cracked patches on the palms | Often chronic; friction and pressure can worsen it |
Many people have a mix, for example atopic skin that is then damaged by wet work. For blistering hand eczema, see the full guide to pompholyx (dyshidrotic eczema), and for allergic reactions see contact dermatitis. The types of eczema guide explains how they fit together.

What causes hand eczema?
Hand eczema usually develops when the skin barrier is worn down faster than it can repair itself. The most common triggers are:
- Frequent hand washing and wet work. A meta-analysis of 45 studies found that washing hands at least 8 to 10 times a day increased the risk of hand eczema by about 50%, and 15 to 20 times a day by about 66%. Using alcohol-based hand sanitiser was not linked to a higher risk (Loh and Yew, 2022).
- Jobs with wet or dirty work, such as healthcare, hairdressing, cleaning, catering, construction and caring for young children.
- Detergents, solvents and cleaning products that strip the skin's natural oils.
- Contact allergens. In a French study of 279 glove-wearing patients with hand eczema, almost a third reacted to their own gloves or to glove chemicals, mostly rubber accelerators (Clément et al., 2023).
- Cold, dry weather, which makes cracking worse in winter.
- A personal history of atopic eczema, which makes the barrier more fragile.
How is hand eczema diagnosed?
A doctor diagnoses hand eczema by looking at the skin and asking about your work, hobbies, products and other skin problems. Because allergies are a common hidden cause, European guidelines recommend patch testing for people with hand eczema that lasts or keeps coming back (Thyssen et al., 2022). Patch testing finds allergens such as glove chemicals, preservatives and fragrance so you can avoid them. A skin scraping may be taken if a fungal infection is possible, because fungal infections can look similar but need different treatment.
How is hand eczema treated?
Treatment is usually a step-by-step plan. A Cochrane review of 60 trials found that topical corticosteroids and UV light therapy are standard treatments, but many studies were small, and the evidence does not clearly favour one specific treatment over another (Christoffers et al., 2019).
- Skin care and protection for everyone: regular emollients, gloves for wet work, and avoiding triggers and allergens. This is the foundation at every stage (Thyssen et al., 2022).
- Anti-inflammatory creams for flares: a short course of a prescription steroid cream, then less often to keep it under control. Tacrolimus ointment is a non-steroid option.
- Delgocitinib cream: a newer non-steroid JAK inhibitor cream for moderate to severe chronic hand eczema. In two phase 3 trials, 20% and 29% of patients were clear or almost clear after 16 weeks, compared with 10% and 7% using the plain cream base (Bissonnette et al., 2024).
- For severe cases: a dermatologist may use alitretinoin tablets, phototherapy or other systemic treatments. Alitretinoin had high-certainty evidence of benefit over placebo in the Cochrane review (Christoffers et al., 2019).
Many people want to keep strong steroid creams short. See natural and steroid-free alternatives to steroid cream and QICAOGANGMU vs steroid creams.

Steroid-free care for dry, itchy hands. QICAOGANGMU pairs Ku Shen and She Chuang Zi with cooling borneol and menthol, tested steroid-free by TÜV SÜD PSB. Rated 4.5 to 4.7 out of 5 on Amazon. See the formula
A daily routine to heal hand eczema

- Wash with lukewarm water and a mild, fragrance-free cleanser, only as often as you need to.
- Pat dry gently, including between the fingers and under rings.
- Moisturise straight after every wash, using a thick cream or ointment. Keep a tube by every sink and in your bag.
- Use alcohol hand rub when hands are not visibly dirty, instead of extra washing.
- Wear gloves for wet work and cleaning, with thin cotton liners underneath, and take them off as soon as you finish so sweat does not build up.
- Take off rings for wet work, because soap and water get trapped underneath.
- Wear warm gloves outdoors in cold, dry weather.
- Apply a thicker layer at night, under cotton gloves, to help cracks heal.
- Do not scratch or pick at cracks; cool the itch with a cold compress or a cooling cream instead.
- Keep going when the skin looks better, because the barrier takes weeks to fully recover.
More tips: how to stop itching naturally and the guide to choosing a natural eczema cream.
When should you see a doctor?
- It does not improve after 2 to 4 weeks of careful skin care
- It keeps coming back or affects your work or sleep
- Cracks are deep and painful, or the skin is weeping, crusted or yellow, which can mean infection
- You notice a pattern with gloves, products or work materials, which may mean an allergy that needs patch testing
- Only one hand is affected, or the rash spreads to the nails or other parts of the body
Where QICAOGANGMU fits
QICAOGANGMU Steroid-Free Herbal Cream
4.7/5 (243 ratings) and 4.5/5 (666 ratings) on Amazon. Read reviews
QICAOGANGMU is steroid-free daily care for dry, itchy hands: She Chuang Zi 3%, Bing Pian (borneol) 2%, Ku Shen 1.5%, Bai Bu 0.5% and menthol 0.5% in a moisturising glycerin and petrolatum base, which helps hold moisture in the skin. Use a thin layer on intact skin after washing, between flares and alongside your doctor's treatment. The cooling ingredients can sting open cracks or weeping skin, so wait until these have healed, and patch test first.
- Steroid-free: TÜV SÜD PSB found none of 8 corticosteroids (lab reports)
- Fully declared formula: every active ingredient and its percentage on the label
- 100-day money-back guarantee
- US shipping in 2 to 6 business days, free over US$20
Patch test on a small area first, use a thin layer on intact skin and avoid the eyes, lips and genitals. Steroid-free options · Product details
Frequently asked questions
What is the fastest way to heal hand eczema?
Protect the skin barrier first: moisturise after every wash, wear gloves for wet work and avoid irritants. For a flare, a doctor may prescribe a short course of an anti-inflammatory cream. Most people improve within a few weeks, but chronic hand eczema needs ongoing care.
Why does my hand eczema keep coming back?
The most common reasons are ongoing wet work or frequent washing, a hidden contact allergy, stopping skin care once the skin looks better, and a history of atopic eczema. Patch testing can identify allergies.
Is hand eczema contagious?
No. Hand eczema is an inflammatory skin condition and cannot spread to other people. If the skin becomes infected, the infection itself needs treatment.
Does hand sanitiser make hand eczema worse?
In a large review, frequent hand washing raised the risk of hand eczema, while alcohol-based hand rub was not linked to a higher risk. It may sting broken skin, so moisturise afterwards.
Can I use QICAOGANGMU on hand eczema?
Yes, as a steroid-free cream on intact, dry or itchy skin, alongside your doctor's treatment. Avoid open cracks and weeping skin until they heal, and patch test first.
Related articles
References
- Thyssen JP, Schuttelaar MLA, Alfonso JH, et al. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis. 2022;86(5):357-378. PMID 34971008
- Quaade AS, Simonsen AB, Halling AS, Thyssen JP, Johansen JD. Prevalence, incidence, and severity of hand eczema in the general population: a systematic review and meta-analysis. Contact Dermatitis. 2021;84(6):361-374. PMID 33548072
- Loh EW, Yew YW. Hand hygiene and hand eczema: a systematic review and meta-analysis. Contact Dermatitis. 2022;87(4):303-314. PMID 35460528
- Christoffers WA, Coenraads PJ, Svensson Å, et al. Interventions for hand eczema. Cochrane Database Syst Rev. 2019;4(4):CD004055. PMID 31025714
- Bissonnette R, Warren RB, Pinter A, et al. Efficacy and safety of delgocitinib cream in adults with moderate to severe chronic hand eczema (DELTA 1 and DELTA 2): results from multicentre, randomised, controlled, double-blind, phase 3 trials. Lancet. 2024;404(10451):461-473. PMID 39033766
- Clément A, Ferrier le Bouëdec MC, Crépy MN, et al. Hand eczema in glove-wearing patients. Contact Dermatitis. 2023;89(3):143-152. PMID 37331721
Product information. This article is educational and does not replace medical advice. QICAOGANGMU is a topical herbal skin-care cream and does not cure hand eczema. See a doctor for hand eczema that persists, is painful, weeping or infected.


