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Athlete’s Foot: How QICAOGANGMU Combats Tinea Pedis Effectively

Athlete’s Foot: How QICAOGANGMU Combats Tinea Pedis Effectively

By Ava Huang, Herbal Science Researcher at Qicaogangmu

Athlete's foot, medically known as tinea pedis, is a common fungal infection of the feet, primarily affecting the skin between the toes, on the soles, or on the sides of the feet. Characterized by itching, burning, redness, scaling, and sometimes blisters or cracking, it can be highly uncomfortable and, if left untreated, can spread to other parts of the body or to other individuals. This persistent fungal infection often thrives in warm, moist environments, making athletes, individuals who wear tight, non-breathable shoes, and those who frequent public showers or locker rooms particularly susceptible.

While conventional treatments for athlete's foot typically involve topical antifungal creams, these can sometimes require prolonged application, and concerns about recurrence or the desire for gentler alternatives have grown. This has led to a significant demand for natural, steroid-free solutions that can effectively combat the fungal infection, soothe irritated skin, and promote healing without the drawbacks of synthetic compounds. This comprehensive article will delve into the types, causes, and symptoms of athlete's foot, explore the limitations of conventional treatments, and introduce QICAOGANGMU Caoben Yijun Rugao as a leading natural solution. Drawing on both scientific understanding and Traditional Chinese Medicine (TCM) principles, we will illuminate how this herbal cream works to combat tinea pedis effectively, providing a natural path to clear, healthy, and comfortable feet.

Understanding Athlete’s Foot (Tinea Pedis): The Fungal Invader

Athlete's foot is caused by dermatophytes, a group of fungi that thrive on keratin, a protein found in skin, hair, and nails. The most common culprits are *Trichophyton rubrum*, *Trichophyton mentagrophytes*, and *Epidermophyton floccosum*. This infection is highly contagious and can spread through direct contact or by walking barefoot in contaminated areas.

Types of Athlete's Foot:

  • Interdigital Tinea Pedis: The most common form, typically occurring between the fourth and fifth toes. It presents as itching, burning, redness, scaling, and maceration (softening and breakdown of skin) [1].
  • Moccasin-Type Tinea Pedis: Affects the soles of the feet, extending up the sides like a moccasin. Characterized by chronic dryness, scaling, and thickening of the skin, often with mild redness.
  • Vesicular Tinea Pedis: Less common, characterized by fluid-filled blisters (vesicles) on the sole or top of the foot, often accompanied by itching and burning.

Common Causes and Risk Factors:

  • Warm, Moist Environments: Fungi thrive in damp, dark places. Tight, non-breathable shoes and sweaty feet create ideal conditions.
  • Public Places: Walking barefoot in public showers, locker rooms, swimming pools, and gyms.
  • Footwear: Wearing socks made of non-absorbent materials (e.g., nylon) or shoes that don't allow feet to breathe.
  • Compromised Skin Barrier: Small cuts, cracks, or excessive dryness can make the skin more susceptible to fungal invasion.
  • Weakened Immune System: Individuals with diabetes or compromised immune systems may be more prone to infections.

Recognizing the Symptoms:

Symptoms can vary but commonly include:

  • Itching: Often intense, especially after removing shoes and socks.
  • Burning or Stinging Sensation: Particularly between the toes or on the soles.
  • Redness: Inflamed skin.
  • Scaling and Peeling: Dry, flaky skin.
  • Cracking and Fissures: Especially between the toes, which can be painful and lead to secondary bacterial infections.
  • Blisters: Fluid-filled bumps, particularly in vesicular tinea pedis.
  • Odor: Unpleasant foot odor due to bacterial overgrowth in moist conditions.

Early identification and consistent treatment are crucial to prevent the spread of the infection and alleviate discomfort.

Limitations of Conventional Treatments for Athlete’s Foot

Conventional medical treatments for athlete's foot primarily involve topical antifungal medications. While generally effective, they often come with limitations that lead many individuals to seek alternative or complementary solutions.

1. Topical Antifungal Creams:

  • Examples: Imidazoles (e.g., clotrimazole, miconazole, ketoconazole), allylamines (e.g., terbinafine, naftifine).
  • Mechanism: These drugs inhibit fungal growth or kill fungi by interfering with their cell membrane synthesis.
  • Benefits: Highly effective, with terbinafine and azoles curing 70-75% of tinea pedis cases compared to 20-30% with placebo [4]. Magenta (Castellani) paint is also noted as an effective topical treatment [1].
  • Limitations/Drawbacks:
    • Duration of Treatment: Often require consistent application for 2-4 weeks, even after symptoms resolve, to prevent recurrence. Non-adherence is common.
    • Recurrence: Despite high cure rates, recurrence is common if predisposing factors (e.g., moist feet, contaminated shoes) are not addressed.
    • Side Effects: Generally mild, but can include local irritation, burning, stinging, or redness.
    • Not for All Fungi: May not be effective against all types of fungal infections or mixed infections.

2. Oral Antifungals:

  • Examples: Terbinafine, itraconazole, fluconazole.
  • Mechanism: Systemically target the fungal infection.
  • Benefits: Used for severe, widespread, or chronic cases, or when topical treatments fail.
  • Limitations: Carry risks of systemic side effects (e.g., liver issues, gastrointestinal upset, drug interactions) and require medical supervision.

3. Other Topical Agents:

  • Tea Tree Oil:
    • Mixed Evidence: Some studies show a 10% tea tree oil cream reduces tinea pedis symptoms similarly to tolnaftate 1%, but not more effectively than placebo [3]. However, a randomized trial of 25-50% tea tree oil showed 68-72% clinical improvement vs. 39% placebo, with 64% mycological cure at 50% concentration [5]. A comprehensive review, however, suggests tea tree oil is "likely ineffective" in few high-quality studies [4]. Herbal foot baths, including those with tea tree oil, are commonly used, though scientific evidence is still developing [2].

General Limitations of Conventional Treatments:

  • Focus on Fungus, Not Skin Health: While effective at killing fungi, they may not fully support the skin's barrier repair or address the inflammation and discomfort holistically.
  • Potential for Irritation: Some synthetic antifungals can be irritating to already compromised skin.
  • Lack of Immediate Symptomatic Relief: While they work to cure the infection, immediate relief from itching and burning may not be as pronounced as desired.

These limitations highlight the critical need for safe, gentle, and effective steroid-free alternatives that can not only combat the fungal infection but also provide sustained relief from symptoms, reduce inflammation, and support the skin's natural healing processes. This is where natural remedies and Traditional Chinese Medicine offer a promising and holistic approach.

The Power of Natural Approaches for Fungal Skin Infections

The increasing demand for gentle yet effective solutions for fungal skin infections like athlete's foot has led to a significant interest in natural and complementary approaches. These methods often harness the power of botanical compounds and traditional wisdom to combat fungi, reduce inflammation, soothe irritation, and support skin repair, often with fewer adverse effects than synthetic treatments.

Core Principles of Natural Treatment for Fungal Infections:

  • Antifungal Properties: Many plant-derived compounds possess inherent antifungal effects that can directly inhibit the growth of dermatophytes.
  • Anti-Inflammation: Natural ingredients can help calm the redness, swelling, and burning sensation associated with fungal infections.
  • Antipruritic Action: Specific natural compounds can alleviate the intense itching, helping to break the itch-scratch cycle and prevent secondary damage.
  • Skin Barrier Support: Natural emollients and healing compounds can help repair the skin's compromised barrier, improving its resilience against future infections and promoting overall skin health.
  • Astringent/Drying Effects: Some botanicals can help dry out moist areas, making the environment less hospitable for fungal growth.

Evidence Supporting Botanicals and Natural Compounds in Fungal Relief:

  • Ajoene (Garlic Extract): A cream derived from garlic extract (0.4% ajoene) achieved a remarkable 79% clinical and mycological cure rate in tinea pedis after just 7 days in a study [6]. This highlights the potent antifungal capabilities of natural compounds.
  • Herbal Foot Baths: Herb-based foot baths have shown promise, improving symptoms, clearance rates, and quality of life in tinea pedis patients [7]. This suggests that a combination of beneficial plant extracts can be highly effective.
  • Coriander Oil: A 6% coriander oil in ointment significantly improved interdigital tinea pedis clinical signs and reduced fungal cultures over 28 days [8].
  • Tea Tree Oil (*Melaleuca alternifolia*): As noted, while some reviews are cautious, specific trials with higher concentrations (25-50%) of tea tree oil have shown clinical and mycological improvement for tinea pedis [5]. Its known antiseptic and anti-inflammatory properties contribute to its use in various skin conditions.
  • General Herbal Extracts: Herbal foot baths, which often contain a mix of herbal extracts, are commonly used for athlete's foot [2], indicating traditional recognition of their benefits.

By leveraging the multi-targeted actions of these natural compounds—combating fungi, reducing inflammation, and supporting skin repair—natural remedies offer a promising path for managing fungal skin infections, often with a more favorable side effect profile compared to conventional treatments.

QICAOGANGMU: Your Natural, Steroid-Free Solution for Athlete’s Foot

QICAOGANGMU Caoben Yijun Rugao offers a unique, natural, and steroid-free approach to effectively combating athlete's foot (tinea pedis). Rooted in the principles of Traditional Chinese Medicine (TCM), it aims to address the core imbalances that manifest as fungal infections, primarily "Damp-Heat" in the lower limbs, leading to moisture, inflammation, and fungal proliferation. QICAOGANGMU is formulated to clear these pathogenic factors, eliminate fungi, reduce inflammation, alleviate itching, and support the skin's natural healing processes.

Key Herbal Ingredients in QICAOGANGMU for Athlete’s Foot Relief:

The synergistic blend of meticulously selected natural ingredients in QICAOGANGMU provides comprehensive relief by targeting multiple aspects of tinea pedis pathology:

  • 苦参 (Ku Shen) / Sophora flavescens (Sophora Root): A cornerstone herb in TCM for clearing "Damp-Heat" and "Wind." It is widely recognized for its potent anti-inflammatory, anti-bacterial, and crucially, anti-fungal properties. Its compounds can directly inhibit fungal growth and reduce the inflammation (redness, burning) associated with athlete's foot. Studies show *Sophora flavescens* extracts have strong antipruritic action by reducing itching [9].
  • 蛇床子 (She Chuang Zi) / Cnidii Fructus (Cnidium Fruit): Highly valued in TCM for dispelling "Wind" and "Dampness" and for its strong antipruritic (itch-relief), anti-allergic, and direct antifungal actions. It directly targets the intense itching and helps eliminate the fungal pathogens responsible for athlete's foot. A comprehensive review details its pharmacology, highlighting its strong antipruritic and antifungal effects relevant to skin conditions [10].
  • 冰片 (Bing Pian) / Borneolum Syntheticum (Synthetic Borneol): A powerful penetrating agent that enhances the absorption of other active ingredients into the deeper layers of the skin, ensuring faster and more effective delivery of the antifungal and anti-inflammatory compounds directly to the site of infection. It also possesses properties that reduce swelling and act as a mild antiseptic, helping to keep the infected area clean and reduce discomfort. Borneol's analgesic effects also contribute to pain relief [11]. Studies show Borneol significantly reduces acute and chronic itch in mice and patients by modulating TRPA1 and TRPM8 ion channels [14].
  • 薄荷脑 (Bo He Nao) / Menthol: Provides an immediate cooling sensation, anti-itch, and pain relief, offering instant comfort from the burning, itching, and heat often associated with athlete's foot. Menthol's benefits extend to supporting wound healing by reducing inflammatory cytokines and boosting antioxidant enzymes [12], which is beneficial for cracked or peeling skin. It's a widely recognized antipruritic agent for various skin conditions [13].

This powerful combination in QICAOGANGMU works synergistically to directly combat fungal growth, reduce inflammation, alleviate itching and burning, promote skin healing, and create an unfavorable environment for fungal recurrence. As a steroid-free formulation, it offers a safe and effective long-term solution without the concerns of conventional treatments, making it ideal for combating tinea pedis effectively.

How to Use QICAOGANGMU for Athlete’s Foot Relief

For optimal results and to ensure safe application, adhere to the following instructions when incorporating QICAOGANGMU Caoben Yijun Rugao into your athlete's foot management routine:

  1. Cleanse and Dry Feet Thoroughly: Wash your feet daily with mild soap and lukewarm water. Pay special attention to the areas between the toes. After washing, dry your feet completely, especially between the toes, by gently patting with a clean towel. Moisture is a fungal friend, so thorough drying is crucial.
  2. Perform a Patch Test (First Use): Before widespread application, especially if you have sensitive skin or are prone to allergies, conduct a patch test. Apply a tiny amount (e.g., a pea-sized drop) of QICAOGANGMU to a small, inconspicuous area of skin (e.g., on the top of your foot, away from the affected area) once a day for 2-3 days. Monitor the area closely for any signs of adverse reactions such as increased redness, itching, burning, or new rash. If no irritation occurs, you may proceed with wider application.
  3. Apply a Thin, Even Layer: Squeeze a small amount of cream onto your fingertip. Gently spread a thin, even layer directly over the affected areas (between toes, on soles, or sides of feet). Ensure the cream covers all areas showing symptoms. Do not rub vigorously or apply excessively thick layers; a thin, consistent application is sufficient for efficacy. Ensure the cream is fully absorbed before putting on socks or shoes.
  4. Frequency of Application: Apply the cream 2-3 times daily, or as directed by your healthcare professional. Consistency is paramount for achieving and maintaining results. Apply in the morning after showering, before bedtime, and after any activity that makes your feet sweaty.
  5. Maintain Hand Hygiene: Always wash your hands thoroughly with soap and water both before and after applying the cream to prevent the spread of the fungal infection to other body parts or individuals.

Duration of Use:

Athlete's foot often requires consistent treatment. Continue using QICAOGANGMU for at least 2-4 weeks, even if symptoms appear to resolve sooner. This helps ensure the complete eradication of the fungal infection and reduces the chance of recurrence. For chronic or recurrent cases, prolonged use as a preventive measure may be beneficial. Always consult a healthcare professional if your symptoms do not improve, worsen, or if you have concerns about long-term management.

Safety and Considerations When Using Natural Athlete’s Foot Treatments

While QICAOGANGMU Caoben Yijun Rugao is formulated with natural herbal ingredients and designed to provide gentle and effective relief for athlete's foot, it is essential to approach any topical treatment with an understanding of general safety and specific considerations. Even natural products can elicit individual sensitivities or may not be suitable for all situations.

General Safety Precautions for Topical Applications:

  • For External Use Only: This product is intended solely for external application to the skin. Avoid direct contact with eyes, inside the mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with clean water.
  • Patch Test is Mandatory: As highlighted in the "How to Use" section, always perform a patch test before widespread application. This is especially crucial for individuals with sensitive skin or a history of allergies or skin reactivity. Discontinue use immediately if any signs of irritation, increased redness, burning, itching, or rash develop.
  • Store Properly: To maintain product efficacy and shelf-life, store QICAOGANGMU in a cool, dry place, away from direct sunlight and excessive heat. Keep it out of reach of children and pets.
  • Check Expiry Date: Ensure the product is used before its expiry date. The effectiveness and safety of ingredients cannot be guaranteed beyond this period.

Specific Considerations for Athlete’s Foot Treatment:

  • Differentiate from Other Conditions: Ensure your foot condition is indeed athlete's foot. Other conditions like eczema, psoriasis, or bacterial infections can mimic its symptoms. If unsure, consult a healthcare professional for an accurate diagnosis.
  • Secondary Bacterial Infections: Cracked or macerated skin from athlete's foot can become infected by bacteria. If you notice signs of bacterial infection (e.g., increased pain, pus, spreading redness, fever), QICAOGANGMU may not be sufficient, and you should seek medical advice for potential antibiotic treatment.
  • Nail Involvement (Onychomycosis): If the fungal infection has spread to your toenails (onychomycosis), characterized by thickened, discolored, or crumbling nails, topical creams alone are often insufficient. Nail fungus typically requires oral antifungal medication or specialized laser treatments. Consult a podiatrist or dermatologist.
  • Diabetes and Compromised Circulation: Individuals with diabetes or poor circulation should be particularly cautious with any foot condition. Even minor infections can lead to serious complications. Always consult a healthcare professional for athlete's foot if you have these underlying conditions.
  • Pregnancy and Breastfeeding: Although topical application typically results in minimal systemic absorption, pregnant or breastfeeding individuals should always consult their doctor or a qualified healthcare professional before using any new topical product, including herbal creams, to ensure safety for both mother and child.
  • Children: Athlete's foot can occur in children. For use on pediatric patients, it is highly recommended to seek advice from a pediatrician or dermatologist before application.
  • Allergies to Botanicals: Despite being natural, some individuals may have allergies or sensitivities to specific botanical ingredients (e.g., Menthol, Sophora flavescens, Cnidii Fructus). The patch test is crucial to identify such sensitivities. Review the ingredient list thoroughly if you have known allergies.

By understanding and adhering to these safety guidelines and integrating them with professional medical advice when needed, individuals can make informed choices about their athlete's foot treatment, leveraging the benefits of QICAOGANGMU Caoben Yijun Rugao effectively and safely, working towards healthier, clear, and comfortable feet.

Holistic Management for Athlete’s Foot: Prevention and Beyond

Effective long-term management of athlete's foot extends beyond topical creams alone. It demands a comprehensive, holistic approach that focuses on meticulous foot hygiene, environmental control, and preventive measures to break the cycle of infection and recurrence. This strategy perfectly complements the antifungal and healing actions of natural solutions like QICAOGANGMU.

Crucial Hygiene and Environmental Practices:

  • Keep Feet Clean and Dry: Wash your feet daily with soap and water, and dry them thoroughly, especially between the toes. This is the single most important step.
  • Change Socks Regularly: Change socks daily, or more often if your feet sweat heavily. Opt for socks made of moisture-wicking materials (e.g., cotton, wool, or synthetic blends designed for athletic use).
  • Choose Breathable Footwear: Wear shoes made of breathable materials (e.g., leather, canvas) and avoid tight-fitting or synthetic shoes that trap moisture. Alternate shoes daily to allow them to dry out completely.
  • Go Barefoot When Possible: At home, allow your feet to air out by going barefoot or wearing open-toed sandals.
  • Protect Feet in Public Places: Wear shower sandals or flip-flops in public showers, locker rooms, swimming pools, and gyms to avoid direct contact with contaminated surfaces.
  • Disinfect Footwear: Regularly clean and disinfect your shoes using antifungal sprays or powders. Sunlight can also help dry out shoes and kill fungi.

Lifestyle Considerations:

  • Manage Underlying Conditions: If you have diabetes or a compromised immune system, strict management of these conditions is crucial, as they can increase susceptibility to fungal infections.
  • Avoid Sharing: Do not share towels, socks, shoes, or nail clippers, as these can spread the infection.
  • Avoid Scratching: While tempting, scratching can spread the infection to other body parts (e.g., groin, hands) or introduce bacteria, leading to secondary infections. Use QICAOGANGMU or cool compresses for itch relief.

When to Seek Professional Medical Advice:

While adopting natural and holistic approaches can be highly effective, it is vital to consult a podiatrist or dermatologist if:

  • Symptoms do not improve significantly within 2-4 weeks of consistent natural treatment and diligent hygiene.
  • The infection spreads to your toenails, hands, or other body parts.
  • You develop signs of a bacterial infection (e.g., increased pain, swelling, pus, fever, red streaks).
  • You experience severe pain, extensive blistering, or open sores.
  • You have diabetes, poor circulation, or a weakened immune system, as foot infections can lead to serious complications.
  • You have recurrent episodes that significantly impact your quality of life, as an underlying cause may need to be identified and addressed.

By combining rigorous hygiene and preventive measures with the targeted antifungal and healing properties of QICAOGANGMU, individuals can effectively combat athlete's foot and work towards sustained clear, healthy, and comfortable feet.

Conclusion: QICAOGANGMU — Your Natural Path to Healthy Feet

Athlete's foot, a persistent and uncomfortable fungal infection, often requires more than just temporary relief. While conventional antifungal treatments are effective, concerns about recurrence and the desire for gentler, sustainable solutions have highlighted the profound value of natural and holistic approaches.

QICAOGANGMU Caoben Yijun Rugao stands as a powerful natural solution for athlete's foot. Rooted deeply in the time-honored principles of Traditional Chinese Medicine and supported by scientific evidence, its synergistic blend of potent herbal ingredients—including Sophora flavescens, Cnidii Fructus, Borneol, and Menthol—works comprehensively. It directly combats fungal growth, reduces inflammation, alleviates intense itching and burning, and actively supports the skin's natural healing and barrier processes. As a steroid-free formulation, QICAOGANGMU offers a gentle yet profoundly effective path to relief, making it ideal for continuous, long-term use without concerns of harshness or side effects.

By integrating QICAOGANGMU into a holistic management strategy—one that embraces diligent foot hygiene, proper footwear, and proactive prevention—you can empower yourself to effectively combat tinea pedis. Choose QICAOGANGMU to work harmoniously with your body, leading to the lasting comfort, clarity, and confidence of healthy feet you truly deserve.

Combat Athlete’s Foot Naturally: Choose QICAOGANGMU!

Tired of the itching, burning, and discomfort of athlete’s foot? Seeking a natural, steroid-free solution? QICAOGANGMU Caoben Yijun Rugao offers a gentle yet powerful herbal cream, expertly crafted with traditional Chinese herbs to effectively combat tinea pedis, soothe irritated skin, and restore healthy feet.

Who it helps: Ideal for anyone experiencing athlete’s foot symptoms (itching, burning, peeling, cracking), especially those concerned about conventional treatment side effects or looking for a sustainable, natural option for daily foot comfort and fungal prevention.

Why it's safe/trusted: Rooted in centuries of herbal wisdom and committed to natural purity, QICAOGANGMU provides a trustworthy and effective path to clear, comfortable, and healthy feet. Embrace a holistic approach to foot wellness!

Take the natural step towards healthy feet:

We are so confident in our product that we offer a 100-Day Money-Back Guarantee. Try QICAOGANGMU risk-free and rediscover the comfort of healthy feet.

"My athlete's foot was stubborn and kept coming back. This QICAOGANGMU cream is amazing! The itching stopped almost immediately, and my feet are finally clear. It's so much better than harsh chemical creams."

Athlete's Foot Sufferer, November 2025

"I love that this is a natural option for athlete's foot. It's gentle, very effective, and keeps my feet comfortable even after long runs. A true game-changer for foot health!"

Active User, October 2025

References

  1. Gupta AK, et al. Magenta (Castellani) paint and imidazoles (e.g., clotrimazole, ketoconazole, terbinafine) are effective topical treatments for tinea pedis. StatPearls (NCBI). 2023. NCBI Bookshelf Link (Evidence Level: Review Article/Medical Textbook)
  2. Herbal foot baths (e.g., vinegar, herbal extracts, tea tree oil) are commonly used, though evidence for tea tree oil remains unproven in few high-quality studies. NCBI Bookshelf. 2022. NCBI Bookshelf Link (Evidence Level: Review Article/Medical Textbook)
  3. Tong MM, et al. Tea tree oil cream (10%) reduces tinea pedis symptoms similarly to tolnaftate 1%, though not more effective than placebo. Australasian Journal of Dermatology. 1992;33(3):145–149. PMID: 1303075. PMID: 1303075 (Evidence Level: Clinical Study)
  4. Pazyar N, et al. Topical antifungals (terbinafine, clotrimazole, etc.) cure 70–75% of tinea pedis vs. 20–30% with placebo; tea tree oil likely ineffective. Molecules. 2022;27(3):1048. PMCID: PMC7822611 (Evidence Level: Review Article)
  5. Satchell AC, et al. A randomized trial of 25–50% tea tree oil showed 68–72% clinical improvement vs. 39% placebo; 64% mycological cure with 50% concentration. BMJ. 1992;305(6860):898–900. PMID: 12121393. PMID: 12121393 (Evidence Level: Clinical Study, Randomized Trial)
  6. Ledezma E, et al. Ajoene cream, derived from garlic extract (0.4%), achieved a 79% clinical and mycological cure in tinea pedis after 7 days. Journal of the American Academy of Dermatology. 2000;43(5 Pt 1):821–824. PMID: 9009665. PMID: 9009665 (Evidence Level: Clinical Study)
  7. Li H, et al. Herb-based foot baths improved symptoms, clearance rate, and quality of life in tinea pedis patients. PubMed. 2024;40501260. PMID: 40501260 (Evidence Level: Clinical Study)
  8. Nair B, et al. Coriander oil (6%) in ointment significantly improved interdigital tinea pedis clinical signs and reduced fungal cultures over 28 days. Journal of Dermatological Treatment. 2013;24(6):448–452. PMID: 23466353. PMID: 23466353 (Evidence Level: Clinical Study)
  9. Li ZY, et al. Antipruritic effect of Sophora flavescens on mouse dermatitis models. Journal of Ethnopharmacology. 2010 Apr 21;128(3):658-664. PMID: 20300958. PMID: 20300958 (Evidence Level: In Vivo Study)
  10. Tang B, et al. Chemical constituents and pharmacological activities of Cnidium monnieri (L.) Cuss. Molecules. 2020 Jan 29;25(3):575. PMID: 32028721. PMID: 32028721 (Evidence Level: Review Article)
  11. He J, et al. Topical borneol alleviated inflammation and pain by inhibiting macrophage/lymphocyte infiltration and downregulating IL‑6, TNF‑α, IL‑8. Journal of Pain Research. 2020 Jan 20;13:163–172. PMID: 31978868. PMID: 31978868 (Evidence Level: In Vivo Study)
  12. Jamal N, et al. Menthol-based cream enhanced wound healing in rats by decreasing TNF‑α & IL‑6, boosting antioxidant enzymes, and reducing inflammation. Pharmaceutical Biology. 2021 Dec;59(1):1532–1539. PMID: 34834317. PMID: 34834317 (Evidence Level: In Vivo Study)
  13. Derma UK. The Benefits of Menthol. Menthoderm. 2017. Derma UK Link (Evidence Level: Product Information/Review)
  14. Li ZY, et al. Borneol significantly reduced acute and chronic itch in mice and patients by modulating TRPA1 and TRPM8 ion channels. Frontiers in Pharmacology. 2023 Nov 29;14:1288289. PMID: 38103845. PMID: 38103845 (Evidence Level: In Vivo/Clinical Study)

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting any new treatment or if you have any medical concerns. Individual results may vary.

© 2025 Qicaogangmu. All rights reserved.

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